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小動(dòng)物清醒活動(dòng)裝置/清醒動(dòng)物活動(dòng)籠 主要應(yīng)用于動(dòng)物在微透析或者長(zhǎng)期給藥過(guò)程中，保持自由活動(dòng)狀態(tài)。

小動(dòng)物清醒活動(dòng)裝置可以對(duì)清醒狀態(tài)下的大鼠/小鼠進(jìn)行長(zhǎng)時(shí)間的微透析或給藥實(shí)驗(yàn)。通過(guò)容器的旋轉(zhuǎn)來(lái)抵消動(dòng)物活動(dòng)的產(chǎn)生的轉(zhuǎn)動(dòng)力，從而使導(dǎo)管和連接線更不致纏結(jié)扭曲。配合行為學(xué)監(jiān)測(cè)系統(tǒng)還可以監(jiān)測(cè)動(dòng)物的活動(dòng)情況，從而研究動(dòng)物服藥前后活動(dòng)的差異，大大提高了實(shí)驗(yàn)人員的工作效率。

大小鼠清醒活動(dòng)裝置可以使大小鼠在微透析或者長(zhǎng)期給藥過(guò)程中，保持自由活動(dòng)狀態(tài)。 **設(shè)計(jì)的Raturn裝置，可以對(duì)小動(dòng)物在清醒狀態(tài)下進(jìn)行長(zhǎng)時(shí)間的微透析實(shí)驗(yàn)。通過(guò)容器的旋轉(zhuǎn)來(lái)抵消動(dòng)物活動(dòng)的產(chǎn)生的轉(zhuǎn)動(dòng)力，從而使導(dǎo)管和連接線更不致纏結(jié)扭曲。配合行為學(xué)監(jiān)測(cè)系統(tǒng)還可以監(jiān)測(cè)動(dòng)物的活動(dòng)情況，從而研究動(dòng)物服藥前后活動(dòng)的差異，大大提高了實(shí)驗(yàn)人員的工作效率。

Raturn裝置取代了傳統(tǒng)的液體活動(dòng)臂，保證了連續(xù)的液體通路，保證了實(shí)驗(yàn)的連續(xù)性，并大大延長(zhǎng)了清醒活動(dòng)臂的使用壽命。還可以從動(dòng)物身上連出多條管線，在一只動(dòng)物身上完成過(guò)去需要多只動(dòng)物才能完成的實(shí)驗(yàn)，并確保了實(shí)驗(yàn)的可靠性和實(shí)驗(yàn)數(shù)據(jù)的準(zhǔn)確性和穩(wěn)定性。

Sampling Caging Systems

When sampling from awake， freely moving animals， one must ensure the animals don’t hurt themselves or damage your sampling lines. BASi offers two technologies to achieve this; the Raturn interactive caging system， and liquid swivels. The Raturn System is based on technology developed by BASi. However， as a company that prides itself on satisfying our customers， we want to be sure to offer you the options you desire. Depending on your anticipated experimental goals， you may find it more useful to use one type of system over the other. The guide below is intended to help you select the system that best meets your needs.

五通轉(zhuǎn)環(huán)是一個(gè)具備有低的死體積、小旋轉(zhuǎn)力矩，適合于大、小鼠實(shí)驗(yàn)的五通道清醒活動(dòng)裝置。能夠滿足客戶在大鼠清醒活動(dòng)狀態(tài)下完成單位點(diǎn)、雙位點(diǎn)微透析和多點(diǎn)灌流/體液收集等等同步實(shí)驗(yàn)的要求。通道均用特殊材料處理以防止對(duì)神經(jīng)遞質(zhì)或者所觀測(cè)藥物的影響。五通道旋轉(zhuǎn)器包含一個(gè)平衡力臂可*小化動(dòng)物上方垂直的壓力。

液體轉(zhuǎn)環(huán)清醒活動(dòng)系統(tǒng)（ Liquid Swivel-based Systems ）是由2個(gè)小圓柱組成，依靠動(dòng) 物的拖帶轉(zhuǎn)動(dòng)。它需要實(shí)驗(yàn)者非常細(xì)心地調(diào)節(jié)2個(gè)小圓柱的緊密度。即解決漏液和轉(zhuǎn)動(dòng)的矛盾。如果調(diào)節(jié)密封緊，可以不漏液，但是不容易轉(zhuǎn)動(dòng)，堵塞管子。如果調(diào)節(jié)密封松，使轉(zhuǎn)動(dòng)靈活，但是容易漏液，需要防止2個(gè)圓柱之間容易漏液和粘連不動(dòng)；避免管子堵塞。

Liquid Swivel-based Systems

· Swivel systems have been successfully been used for years by researchers in pharma， universities， and CROs.

· Swivels function by using concentric channels for each line that goes into or out of the subject. With each channel that is added to the swivel， the dead volume and the resistance to being turned by the animal increases.

· Swivels contain internal seals which maintain the connection from the top of the swivel to the bottom (these seals require maintenance after each use of the swivel).

· When using a swivel system， it is the swivel itself that turns to prevent twisting of the inlet and outlet lines.

A liquid swivel is satisfactory if:

· You intend to use the system ONLY for a single type of sampling at one time (microdialysis or ultrafiltration or blood sampling)

· There will only be one or two lines plumbed to/from the animal

· The ability to upgrade， or add capability to your existing equipment is not important to you

· You do not wish to use electrical lead lines

· You are not interested in collecting automated animal activity data

· You would like to be able to use a home-cage in your experimental set-up. (Note: If your animal has a brain microdialysis probe or a guide cannula， we do not recommend sampling in a home cage with a descending cage lid.)

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