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無創(chuàng)傷肺功能檢測(cè) Non-invasive Airway Mechanics

本系統(tǒng)提供長(zhǎng)期跟蹤研究的另一種選擇，即可對(duì)同一動(dòng)物進(jìn)行多次跟蹤檢測(cè)。實(shí)驗(yàn)動(dòng)物處于清醒但不能自由活動(dòng)的狀態(tài)。該系統(tǒng)使用雙腔式體積描記器，對(duì)動(dòng)物的頭部和胸部氣流分別進(jìn)行測(cè)定并計(jì)算得出比氣道阻力（ｓＲａｗ）和比氣道傳導(dǎo)率（ｓＧａｗ）。可根據(jù)需要加配霧化給藥系統(tǒng)。

產(chǎn)品特點(diǎn)：

? 可同時(shí)觀測(cè)多只動(dòng)物，并適合長(zhǎng)期跟蹤研究；清潔，完整的設(shè)計(jì)。使用*少的管線連接一個(gè)平臺(tái)就可同時(shí)監(jiān)測(cè)多達(dá)四只動(dòng)物；

? SRaw和SGaw參數(shù)與有創(chuàng)方式測(cè)定的氣道阻力具有高度相關(guān)性；

? 動(dòng)物實(shí)驗(yàn)準(zhǔn)備較全身體積描記法復(fù)雜；

? 一個(gè)平臺(tái)就可應(yīng)用于小鼠，大鼠和豚鼠-只需搭配不同的動(dòng)物腔室即可；

? 自動(dòng)感應(yīng)物種種類和調(diào)整分析設(shè)置；

The EMMS non-invasive airway mechanics system uses a classic Pennock style double-chamber plethysmograph to measure nasal and thoracic flow. The animal is placed in a double-chamber plethysmograph (eg. PLY 230 for guinea pig)， and is restrained in the chamber with a rubber neck collar. This neck collar also provides an airtight seal between the thoracic and nasal chambers. Flow in the two chambers is measured across two pneumotachographs in the plethysmograph wall. A bias flow air supply is used to prevent build-up of CO2 in the plethysmograph， and may also be used to pull aerosol through the nasal chamber.

Parameters Measured

· Specific Airway Resistance

· Specific Airway Conductance

· Tidal Volume

· Minute Volume

· Time of Inspiration

· Time of Expiration

· Peak Expiratory Flow

· Peak Inspiratory Flow

· Respiratory Rate

· Explanations and more parameters

Features

· Up to 8 animals monitored simultaneously

· Completely non-invasive

· No anaesthesia required

· Aerosol can be administered via the nasal chamber

Uses

· Chronic studies

· Suitable for long-term measurements

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