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3D單分子熒光成像系統(tǒng)

直接聯(lián)系

量子科學(xué)儀器貿(mào)易（北京）有限公司

法國

產(chǎn)品規(guī)格型號(hào)

參考報(bào)價(jià)：

面議

關(guān)注度：

598

產(chǎn)品介紹

3D單分子熒光成像系統(tǒng)

abbelight SAFe360是一款基于單分子定位的顯微成像（SMLM）的3D單分子成像系統(tǒng)，它獨(dú)有的DAISY技術(shù)整合了散光技術(shù)和超臨界角光技術(shù)，能夠極大的提高定位精度，達(dá)到**的xyz同時(shí)15nm的定位精度，可以提供清晰度**的三維的亞細(xì)胞結(jié)構(gòu)圖像，**同時(shí)四色成像觀測，可以實(shí)時(shí)研究不同的結(jié)構(gòu)功能蛋白的共定位信息，在單分子水平研究分子動(dòng)力學(xué)反應(yīng)以及細(xì)胞間的相互作用等。

3D單分子熒光成像系統(tǒng)-SAFe 360

設(shè)備參數(shù)

+ 成像模式：PALM、STORM、PAINT、smFRET 、SPT

+ 光源模式：Epi、TIRF、HILO

+ **分辨率：15 nm的XYZ軸分辨率

+ 超大視野：200 × 200 μm2的視野

+ 一次可同時(shí)采集1.2 μm深度圖像信息

+ **圖像深度：10 μm

+ 實(shí)時(shí)漂移矯正

+ **四色同時(shí)成像

+ 活細(xì)胞成像模式

加裝

TIRF

PALM

STORM

SPT

smFRET

......

兼容

Confocal

Spinning-Desk

Widefield

SIM

STED

Now We See......


3D線粒體結(jié)構(gòu)	核孔復(fù)合物

老鼠海馬神經(jīng)元	微管蛋白網(wǎng)絡(luò)

配套試劑

Smart kit

Compatible dyes

• 10 doses per box

• 200 μL per dose

• 30 sec prepartion

• 2 months in a fridge

• 2 weeks on sample

• Atto 488， WGA-AF®488

• AF®532， CF®532， Cy3b

• AF®555， AF®594， CF®555， AF®568， CF®568， Cy5， MemBriteTM 568， TMR

• AF®647， CF®647， AF®680， CF®680， MemBriteTM 640， Actin-stain 670， SiR647

發(fā)表文獻(xiàn)列表

[1] Cabriel， Clément， et al. "Combining 3D single molecule localization strategies for reproducible bioimaging." Nature communications 10.1 (2019): 1980.

[2] Woodhams， Stephen G.， et al. "Cell type–specific super-resolution imaging reveals an increase in calcium-permeable AMPA receptors at spinal peptidergic terminals as an anatomical correlate of inflammatory pain." Pain 160.11 (2019): 2641-2650.

[3] Belkahla， Hanen， et al. "Carbon dots， a powerful non-toxic support for bioimaging by fluorescence nanoscopy and eradication of bacteria by photothermia." Nanoscale Advances (2019).

[4] Denis， Kevin， et al. "Targeting Type IV pili as an antivirulence strategy against invasive meningococcal disease." Nature microbiology 4.6 (2019): 972.

[5] Szabo， Quentin， et al. "TADs are 3D structural units of higher-order chromosome organization in Drosophila." Science advances 4.2 (2018): eaar8082.

[6] Boudjemaa， Rym， et al. "Impact of bacterial membrane fatty acid composition on the failure of daptomycin to kill Staphylococcus aureus." Antimicrobial agents and chemotherapy 62.7 (2018): e00023-18.

[7] Culley， Sian， et al. "Quantitative mapping and minimization of super-resolution optical imaging artifacts." Nature methods 15.4 (2018): 263.

[8] Berger， Stephen L.， et al. "Localized myosin II activity regulates assembly and plasticity of the axon initial segment." Neuron 97.3 (2018): 555-570.

[9] Cabriel， Clément， et al. "Aberration-accounting calibration for 3D single-molecule localization microscopy." Optics letters 43.2 (2018): 174-177.

[10] Bouissou， Ana?s， et al. "Podosome force generation machinery: a local balance between protrusion at the core and traction at the ring." ACS nano 11.4 (2017): 4028-4040.

[11] Sellés， Julien， et al. "Nuclear pore complex plasticity during developmental process as revealed by super-resolution microscopy." Scientific reports 7.1 (2017): 14732.

[12] Bourg， Nicolas， et al. "Direct optical nanoscopy with axially localized detection." Nature Photonics 9.9 (2015): 587.

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